Sam-E 200mg Mood Support Supplement - S-Adenosyl Methionine Sam-E Supplement for Natural Relaxing Mood Boost Brain Support and Liver Detox Cleanse - Vegan Non-GMO and Gluten Free (60 Servings)

I bought these a couple of weeks ago. Originally, I started with Nature Made SAM-e and found that even though they are enteric coated, they caused massive intestinal disruption, gas, cramps etc.. I switched to this one Nature's Craft because I didn't see any complaints on stomach issues plus they are capsules. Erring on the side of caution, I dumped out half the powder of the capsule to start with just to make sure. If you research the net, you will see that some of us are very sensitive to meds and supplements so better to start out slow. Background: My husband's health declined as a retired disabled veteran over 21 years. These last four years were the toughest. I was working full time and also dealing with his issues and appointments. He went on dialysis in 2017 and things got worse from that point on. I'm the type that refuses to acknowledge that I have any issues bigger than what I can fix myself. I have never been on anti-depressants or anxiety medications. However, what I was witnessing in his situation was really destroying me. And realize we had very little family or friends who cared (only my adult daughter). He went in for a surgery that turned into two surgeries in the first week of Jan 2020 and died. Two months later the pandemic hit and that isolated me even MORE. The company I worked for closed its doors. I struggled in 2020 like everyone else financially, emotionally, etc.. I also have back and hip pain as I have gotten older...not bad enough to scream about but enough that it affects me. Arthritis runs in our family and my dad had spinal stenosis at a later age than I do but I figure I'm probably heading in that direction. No doctors will see me anyway right now. So recently I tried the first SAM-e that gave me stomach and intestine issues. Then two weeks ago I got this and am only taking half a capsule and OMG I feel like a new person. More energy, clearer head, my pain is reduced everywhere phenomenally and the anxiety and sadness are gone (different than long term grief which takes time) that kept me feeling paralyzed. I'm 59, by the way. I hope this supplement keeps working because this is the best supplement I have taken along these lines all year. I tried other supplements geared for anxiety, depression, etc. and none of them worked well or gave me weird side effects. This one does what it's supposed to do and no side effects. I take it before lunch and it lasts until late in the evening. Thanks for helping me get back on track after such a trying time in my life!

I take these for my self-diagnosed ASD. I jokingly call them my "SAME" pills because they make me more like everyone else. Regardless of brand. SAM-e just seems to work better if taken an hour or so before a meal. I take all my daily supplements before breakfast. Even if some would be better taken multiple times throughout the day, I can't be bothered with that much scheduling if I can help it.Anyway, after taking I can feel my head clear up and my mood brighten. When taken with food, that effect is muted a bit.You will also want to refrigerate this, if possible. It tends to absorb humidity and clump together in the capsule. I can't say if it's less effective. But seems better when refrigerated... so I guess logic permits.

First bottle i got was excellent the second bottle was a different color ( the product ) but seemed to have the effect I was looking for

SAM-e (S-adenosylmethionine) is a supplement commonly used for mood support, particularly for symptoms of depression and anxiety. It plays a role in the production of neurotransmitters like serotonin, dopamine, and norepinephrine, which are critical in regulating mood. Here are some key points to consider when reviewing SAM-e for mood support:

My second pregnancy really changed my brain chemistry and hormones. I did not experience that the first time, other than the standard stuff everyone jokes about. I had become quick to anger and loose my patience that was much more intense than it should have been. There was a deep, strong anger that would arise when the littlest thing would trigger it. Even in the moment of being so angry I knew it wasn’t normal for me. I had always been pretty easy going and patient before my second pregnancy. I knew something was “off” so I tried these. They worked like a charm. I feel my old self again. I don’t feel like a crazy person watching myself have unnatural outburst anymore. I’m back to my chill self and now I have a normal healthy reaction to events triggering anger. I’m so glad I tried this supplement because it was scary feeling so different all of sudden and not really having a good explanation or knowing what to do. Other than not having such intense anger, I don’t feel any other effects (which is good). No complaints at all. I now have a subscription for it.

I’ve been experiencing a year of constant knee pain, cortisone shots and constant stretching exercises. Dr said she could see slight arthritis but nothing unusual. I was starting to get very down ab the whole thing as there were days I was limping around, struggling to stand up and unable to squat. I’m a young active 58yo and can not imagine the rest of my life this way. I started reading up on fibromyalgia and am convinced I hv it. The pain, occasional hot spots and the fact that it often occurs in middle age, women and there’s no test for it. I decided I needed to manage this pain in the most natural way possible. I found this SAMe! It was typically used for mood enhancement but folks found it helped with the pain of fibromyalgia and arthritis! It’s also a supplement not produced naturally by the body so I needed to take it myself. And it’s OTC!! I’ve been taking it for a little more than a week and though it’s early I am sooo hopeful! My knees feel sooo much better. I’m taking 3 capsules per day spaced out ab one every 8 hrs. I’m feeling so much less pain already and am able to fall asleep more comfortably. I hv also stopped taking the 10mg of Prozac I was in for a little menopausal depression I’ve been experiencing, since the SAMe essentially does the same thing as the low Prozac dosage. I love this product and am excited to see how much better I’ll be feeling in the next few weeks!

most sam-e comes in sealed blister packs, this comes as a bottle of capsules..didn't notice any effects after a few days, took a closer look and noticed the capsules smell really bad, like spoiled milki threw mine out it didn't seem safe to take